Aprazer Sunitinib Sutekast -50 mg

What is Sunitinib Sutekast 50 mg Capsule?

Sunitinib sutekast is sold under the brand name Aprazer. It contains salt called Sunitinib Malate. It is a prescription medicine that is used for adults with pancreatic cancer, gastrointestinal stromal cancer (GIST), and advanced kidney carcinoma cancer. It belongs to a group of drugs called Antineoplastics, Tyrosine kinase inhibitors. This medicine is a multi-specific tyrosine receptor inhibitor. It blocks the activity of vascular endothelial kinase 2 receptors (VEGFR2).

What is Pancreatic cancer?

Pancreatic cancer is usually not predicted until advanced stages because it is hard to detect. The pancreas is a small, hockey stick-shaped gland located behind the stomach. The main role of the pancreas is to help in food digestion and regulate blood sugar levels in the body. The pancreas is involved in maintaining blood sugar levels and makes insulin and glucagon, two hormones that control blood sugar levels. 

• How does pancreatic cancer occur?

Pancreas cancer occurs when changes in the pancreas cells lead to multiplying out of control. A mass of tissues begins ( noncancerous) but later on, this mass becomes malignant i.e, cancerous.  

• What are the symptoms of pancreatic cancer?

Most people don’t experience early signs of pancreatic cancer. But after the progression of the disease, people may experience:

• Upper abdominal pain
• Yellowing of the skin and whites of the eyes
• Tiredness 
• Loss of appetite
• Light colored poop
• Dark colored pee
• Weight loss
• Blood clots in the body
• Itchy skin
• New and worsening diabetes
• Nausea and vomiting

What is a gastrointestinal stromal tumor?

A gastrointestinal stromal tumor is a type of tumor that occurs in the gastrointestinal tract. It is most commonly in the stomach or small intestine. These types of tumors are rare tumors that occur when cells become abnormal and grow out of control. GIST can start anywhere in your digestive tract, from the esophagus to the anus. This tumor is rare among people under 40 years of age.

• What are the signs and symptoms of gastrointestinal stromal tumors (GIST)?

Some people have no symptoms of GIST in the early stage. While other individuals may experience the following symptoms:

• Decreased appetite
• Tiredness
• Stomach pain
• Weight loss
• Vomiting blood
• Blood on or in the stool
• Bowel obstruction
• Difficulty swallowing

What is Kidney carcinoma cancer?

Kidney cancer is a type of cancer that starts in the kidney. Kidney cancer is most common in people between the ages of 65 and 74. The kidneys are a pair of bean-shaped organs, each about the size of a fist. They are attached to the upper back wall of the abdomen and protected by the lower rib cage. One kidney is just to the left and the other just to the right of the backbone. The upper and lower portion of each kidney is called the superior pole and inferior pole.

• How does kidney cancer develop?

Kidney cancer develops when cells in the kidneys change and grow out of control. These cells form a mass called a tumor. Cancer begins when changes in the cells divide out of control. A cancerous tumor can spread to other tissues and vital organs. This stage is called advanced kidney cancer.

• What are the signs and symptoms of kidney cancer?

Kidney cancer may not produce any symptoms in the early stages. But as the tumor grows, symptoms may begin to appear. 

Kidney cancer symptoms may include:

• Blood in your pee
• A lump or mass in your kidney area
• Flank pain
• Tiredness
• Not feeling well
• Loss of appetite
• Weight loss
• Low-grade fever
• High blood pressure
• Anemia
• High calcium

Before taking medicine consult your doctor. Take it once a day with or without food as directed by your doctor. Dose and duration will be decided by the necessity and need of the patient. It depends on the treatment and may change from time to time. You should take medicine as per your doctor’s advice. This medicine is strictly not recommended for children, pregnant women, and breastfeeding mothers. It takes some weeks and months to get a better result. Do not stop taking the medicine before your doctor’s advice.

The most common side effects of this medicine are very high blood pressure, severe headache, confusion, problems with your eyesight, nausea, and vomiting. This medicine may increase your blood pressure. So monitor your blood pressure. You monitor your thyroid gland while taking this medicine. You have also noticed some side effects of weight gain, dry skin, and hair loss.

The benefit of Sunitinib Sutekast 50 mg capsule

• In the treatment of Gastrointestinal stromal tumor

Sunitinib Sutekast 50 mg capsule, is a new treatment option to stop further disease progression and in some cases, even reverse it. It reduced the risk of death by 67%. It kills the cancer cells. It prevents the multiplication and spreading of cancer cells in the body. It reduces the growth of cancer cells in the body.

• In the treatment of Pancreatic cancer

This medicine is effective in the treatment of metastatic well-differentiated pancreatic cancer. It stops the disease progression in adults. It reduces the growth of cancer cells. It stops spreading and multiplication. It kills the cancer cells in the body.

• In the treatment of Kidney cancer

Sunitinib has a better quality. It mediates the disease progression. It reduces the growth of cancer cells. It stops the cancer cells and the multiplication of cancer cells in the body. 

Side effects of Sunitinib sutekast 50 mg 

There are Some major and minor side effects of this medicine. But not all side effects need doctor’s attention. If you may experience any side effects that become serious, You may consult your doctor.

Some of the common side effects of this medicine include

• Nausea
• Vomiting
• Weakness
• Edema (swelling)
• Rash
• Dry skin
• Bleeding 

High blood pressure

• Diarrhea
• Constipation
• Numbness of hands and feet
• Hair loss
• Joint pain
•  Weight loss
• Cough
• Taste change
• Indigestion
• Breathlessness

How is Sunitinib sutekast given?

Always take this medicine as per your doctor’s consultation. The dose of Sutent for the treatment of gastrointestinal stromal tumor and renal cell cancer is one 50 mg oral dose taken once daily on the schedule of 4 weeks on treatment followed by 2 weeks off. It may be taken with or without food. For the pancreas is 37.5 mg taken orally once daily. The dose and duration will decide by your doctor. Do not miss the dose. If you miss a dose skip the missed dose and follow your schedule regularly on the next day. Do not double the dose. Take medicine every day on time as prescribed by your doctor. Many other medicines can affect this medicine so let your doctor know all medications you are using during the treatment.

How does Sunitinib sutekast 50 mg work?

Sunitinib sutekast restricts the movement of multiple receptor tyrosine kinase (RTKs) which are responsible for tumor cell increase and angiogenesis. The medicine minimizes tumor biological processes and activates apoptosis of cancer cells. This leads to tumor shrinkage.