Arsonex Injection

What is Arsonex Injection?

Arsonex Injection contains a salt called Denosumab. It is used to prevent blood-related problems in patients who are suffering from a specific type of tumor that has spread to the bones. It is used for treating Osteoporosis – A giant cell tumor of bones that cannot be treated with surgery. It helps to treat the high blood calcium levels in patients suffering from cancer. This injection works to increase bone strength and prevent bone loss and minimized bone-related problems.

How does denosumab work?

Denosumab is manufactured by Glaxo SmithKline Pharmaceuticals Limited. This injection belongs to a group of medicine called Monoclonal antibodies. Denosumab is in a class of medications called RANK ligand inhibitors. It works to prevent bone loss by blocking a certain receptor in the body to decrease bone breakdown. It works to treat Giant Cell Tumor of Bone (GCTB) by blocking a certain receptor in the tumor cells which slows the tumor growth. It works to treat high calcium levels by decreasing bone breakdown as the breakdown of bones releases calcium.

What is Osteoporosis?

The word “osteoporosis” means “porous bone”. It is a disease that weakens bones. If you have this problem you are at a greater risk for sudden and unexpected bone fractures. 

Osteoporosis means that you have less bone mass and strength. The disease often develops without any symptoms or pain. It is usually not shown until the weakened bones cause painful fractures. Most of these fractures of the hip, wrist, and spine.

• Who can get Osteoporosis?

About 200 million people are estimated to have osteoporosis throughout the world. It occurs in both men and women. Women are four times more likely to develop the disease than men. Currently, about two million men in the U.S. have osteoporosis and twelve million are at risk of developing this condition. Osteoporosis is responsible for more than two million fractures each year. Treatment can slow the rate of bone loss in osteoporosis.

• What are the signs and symptoms of Osteoporosis?

 There are no signs and symptoms of osteoporosis. It is sometimes called a silent disease. You should see the following things:

• Loss of height
• Change in posture
• Shortness of breath
• Bone fractures
• Pain in the lower back

To make this medicine more effective, take an adequate amount of calcium and vitamin D supplements during the treatment with this medicine.

Some common side effects of this medicine include pain in the extremity, musculoskeletal pain, nerve pain, urinary tract infection, constipation, and rash. You may consult your doctor if these side effects may not go and get worse. You can take the help of your doctor to reduce or prevent the symptoms of this medicine. 

What Xgeva Injection benefits?

• Treatment of Osteoporosis

Osteoporosis is a common condition that weakens bones, making them delicate and easy to break. It occurs more in women than men. It occurs in women after menopause. This condition can be treated and minimized with medicine. Xgeva Injection slows down the rate at which bone is broken down in your body. This injection maintains bone density and reduces your risk of breaking a bone. 

You can also improve your bone strength by doing exercises daily, and eating healthy foods containing calcium. Take vitamin D and avoid alcohol and smoking. It gives benefit to your health.

Side effects of Xgeva Injection

There are Some major and minor side effects of this medicine. But not all side effects need doctor attention. If you may experience any side effects that become serious, You may consult your doctor.

Some of the common side effects of this medicine include

• Rash
• Eczema
• Abdominal pain
• Constipation
• Sciatica
• Urinary tract infection
• Upper respiratory tract infection

 How often is Xgeva Injection given?

Always take this medicine as per your doctor’s consultation. It is given in form of an injection by your doctor. Dose and duration will decide your doctor. Do not miss the dose. If you miss a dose skip the missed dose and follow your schedule regularly on the next day. Do not double the dose. Take medicine every day on time as prescribed by your doctor. Much other medicine can affect this, so let your doctor know all the medication you are using during the treatment.

How does Xgeva Injection work to treat osteoporosis?

Xgeva Injection decreases bone resorption ( the process by which osteoclasts break the tissue in bones and release minerals, and calcium into the blood) by preventing osteoclast formation and function and increasing bone mass and strength.