Bendamustine (100mg)

What is bendamustine 100 mg?

Bendamustine Injection is used to treat chronic lymphocytic leukemia (CLL; it is a type of blood cancer of white blood cells). This injection is also used to treat a type of Non- Hodgkin’s lymphoma (NHL: cancer that begins in a type of white blood cell that normally fights infection). This medicine slows the spreading of cancer cells. Bendamustine is in a class of medications called alkylating agents. It works to kill existing cancer cells and limit the growth of new cancer cells. It can be used alone or in combination with other medicines as part of chemotherapy.

What is Non- Hodgkin’s Lymphoma?

Non- Hodgkin’s Lymphoma is a group of blood cancers that usually develop in your lymphatic system. They’re genetic disorders. They happen when genes inside certain cells change. In this case, the affected cells are B- lymphocytes (B-cells) or T- lymphocytes (T- cells) that are part of your immune system. There are more than 70 types of non-Hodgkin lymphomas. 

Treatment depends on whether the lymphoma is slow or fast growing and if it is in one area or many areas. Treatment may include chemotherapy, radiation, immunotherapy, targeted therapy, stem-cell transplantation, surgery, or watchful waiting. 

• What are the signs and symptoms of Non- Hodgkin’s Lymphoma?

Non- Hodgkin’s lymphomas cause many symptoms. These symptoms are common and related to many conditions. You should contact your healthcare provider anytime you notice changes in your body that last for several weeks. Here are common Non- Hodgkin’s symptoms:

• Swollen lymph nodes
• Belly pain or swelling
• Chest pain
• Cough
• Trouble breathing
• Persistent fatigue
• Unexplained fever
• Heavy night sweats
• Unexplained weight loss
• Feeling of fullness.

What is blood cancer?

Blood cancer is a type of cancer that affects your blood cells. Leukemia, lymphoma, and myeloma are some of the most common types of blood cancer. There are also types called MPNs and MDS.

Blood cancer is caused by changes in the DNA within blood cells. This causes the blood cells to start behaving abnormally. In almost all cases these changes are connected to things that are out of control. It happens at any age. It is not genetic.

Symptoms and treatment can be different between children and adults. Over 250,000 people are currently living with blood cancer.

• What are the signs and symptoms of blood cancer?

People with blood cancer may experience a range of symptoms including

• Weight loss 
• Bleeding
• Lumps or swellings
• Shortness of breath
• Night sweats
• Infections
• Fever
• Rash or itchy skin
• Pain in your bones, joints, or abdomen
• Tiredness
• Pale skin

What is Multiple myeloma?

Multiple myeloma is a rare blood cancer that affects your plasma cells. Plasma cells are white blood cells and part of your immune system. Plasma cells make antibodies. These antibodies, called immunoglobulins, help to fight infections. 

Multiple myeloma happens when healthy cells turn into abnormal cells that multiply and produce abnormal antibodies called M proteins. This change starts a situation of medical issues and conditions that can affect your bones, your kidneys, and your body’s ability to make healthy red and white blood cells and platelets.

• What are the signs and symptoms of Multiple myeloma?

The exact causes of multiple myeloma are not known but it is more common in older people. Common symptoms of multiple myeloma may include:

• Bone pain
• Fractures
• Weakness or fatigue
• Weight loss
• Frequent infections and fevers
• Feeling very thirsty
• Frequent urination

Bendamustine Injection is given as an injection into the vein under the doctor’s supervision and should not be self-treated. Before taking medicine consult your doctor. Dose and duration will be decided by the necessity and need of the patient. It depends on the treatment and may change from time to time. You should take medicine as per your doctor’s advice. This medicine is strictly not recommended for children, pregnant women, and breastfeeding mothers. It takes some weeks and months to get a better result. Do not stop taking the medicine before your doctor’s advice.

The most common side effects of these medicines include anemia ( low number of red blood cells), decreased white blood cell count, infection, fatigue, nausea, and vomiting. If these side effects become serious, you should consult a doctor and get relief from the side effects.

The benefit of Bendamustine Injection

• In the treatment of Non- Hodgkin’s Lymphoma (NHL)

Non- Hodgkin’s blood cancer is a cancer of the white blood cells in your body. It is also known as mantle cell lymphoma. White blood cells are those cells that help us to fight infections. Bendamustine Injection helps to restrict cancer growth and also blocks the action of other chemicals that are required for cancer growth and its further spread. To prevent infections, you should wash your hands regularly and avoid crowds. Drink plenty of water and stay hydrated.

• In the treatment of blood cancer

Blood cancer is known as leukemia. It is a cancer of the blood-forming tissues that decreases the body’s ability to fight infection. Bendamustine Injection kills or stops the growth of cancer cells. It prevents the multiplication of cancer cells. It is an effective and powerful medicine, so you should consult its risks and benefits. Avoid drinking alcohol and drink plenty of water and stay hydrated. 

• In the treatment of Multiple myeloma

In multiple myeloma, your body is destroying bone faster than replaced. This makes bones weak and painful and more likely to break. Bendamustine Injection may be prescribed along with other cancer treatments such as chemotherapy. It is an important part of your treatment and increases life expectancy. This medicine will kill the cancerous cells and prevent their further growth. It prevents its multiplication and spreading to other parts of the body. 

Side effects of Bendamustine injection

There are Some major and minor side effects of this medicine. But not all side effects need doctor attention. If you may experience any side effects that become serious, You may consult your doctor.

Some of the common side effects of this medicine include

• Fatigue
• Nausea
• Vomiting
• Mucosal inflammation
• Reduced Blood Platelets
• Decreased white blood cell counts
• Infections 
• Fever

How is Bendamustine Injection given?

Always take this medicine as per your doctor’s consultation. The dose and duration will decide by your doctor. Do not miss the dose. If you miss a dose skip the missed dose and follow your schedule regularly on the next day. Do not double the dose. Take medicine every day on time as prescribed by your doctor. Much other medicine can affect this medicine so let your doctor know all medications you are using during the treatment.

How does Bendamustine Injection work?

This is an anti-cancer medication. It works to damage the genetic material (DNA and RNA) of the cancer cells. This stops the growth and prevents the multiplication of cancer cells.

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