Cresp Injection

What is Cresp Injection?

Cresp Injection contains salt called Darbepoetin alfa. It is used to treat anemia. It is a prescription medicine that is available as an injection. Anemia mostly occurs from kidney disease or chemotherapy. It works to stimulate the bone marrow to produce more red blood cells.

What is the Darbepoetin alfa drug used for?

Darbepoetin is sold under the brand name Cresp Injection. It is manufactured by Dr. Reddy’s Laboratories Limited. Darbepoetin alfa injection is used to treat anemia ( a lower than the normal number of red blood cells) in people with chronic kidney failure ( it is a condition in which the kidney slowly and permanently stops working over some time). It is also used to treat anemia caused by chemotherapy in people with certain types of cancer. It cannot be used in place of a red blood cell transfusion to treat severe anemia and has not been shown to improve tiredness or poor well-being that may be caused by anemia.

 How Anemia occurs?

Anemia occurs when there are not enough healthy red blood cells in your body. Red blood cells carry oxygen through your bloodstream, giving you energy and helping your muscles, bones, and organs work properly. 

Anemia can make you feel weak and tired because you are not getting the energy you need. In normal cases, the oxygen that we breathe passes through our lungs and into the red blood cells.

While in anemia, there are not enough red blood cells to carry this oxygen around the body. 

• What are the Symptoms of anemia?

Anemia can happen with or without symptoms. Many of the symptoms of anemia can also be caused by other problems. The only way to know if you have anemia is to get tested. Some of the symptoms you may experience are:

Dizziness, loss of concentration

Pale skin

Chest pain

Shortness of breath

Fatigue or weakness

Cold intolerance

• How does chronic kidney disease cause anemia?

Anybody causes anemia, but it is very common in people with Chronic Kidney Disease (CKD). 

People with CKD may start to have anemia in the early stages of CKD. It is most common in stages 3-5. Anemia gets worse if your kidneys are not working as well as they should. These persons are more likely to get anemia.

• Common symptoms of anemia in Chronic Kidney Disease (CKD)

You have:

Diabetes

Heart disease

High blood pressure

• How does cancer chemotherapy cause anemia?

Chemotherapy is a standard treatment for many different types of cancer.

The chemicals in chemotherapy drugs mainly target cells that reproduce quickly. Along with cancer cells, these drugs can damage healthy cells. A low red blood cell count caused by these medications is called chemotherapy-induced anemia.

These cells are found in the bone marrow and become red blood cells. If any of these cells are damaged, you can develop a low red blood cell count. Anemia goes away once chemotherapy stops but can lead to serious complications develops.

• What are the signs and symptoms of Chemotherapy-induced anemia?

Signs and symptoms of chemotherapy-induced anemia can be underlying cancer symptoms. 

• These symptoms include:
• Fatigue
• Drowsiness
• Depression
• Shortage of breath 
• Rapid heart rate
• Dizziness

Xgeva Injection is given as an injection by a medical professional. Dose and duration will be decided by the necessity and need of the patient. It depends on the treatment and may change from time to time. You should take medicine as per your doctor’s advice. This medicine is strictly not recommended for children, pregnant women, and breastfeeding mothers. It takes some weeks and months to get a better result. Do not stop taking medicine before your doctor’s advice.

Some of the side effects like high blood pressure and hypersensitivity. There are some the symptoms such as severe headache, problems with your eyesight, nausea, vomiting, or fits.

If these symptoms remain stable and get worse. Inform your doctor to get relief and prevent symptoms.

What is the benefit of cresp Injection?

•  In the treatment of anemia caused by Chronic Kidney Disease (CKD)

Anemia is a condition where your body does not have enough red blood cells to carry oxygen around your body.

While Chronic Kidney Disease (CKD) refers to the loss of normal kidney function over a long period. CKD can lead to anemia. 

Cresp Injection can boost your levels of red blood cells. It reduces the symptoms of anemia such as tiredness and weakness. It improves the life of a person.

• In the treatment of anemia caused by Chemotherapy

A person with has low red blood cell count is termed anemia. Cancer treatment with chemotherapy causes many side effects. One of the most important side effects is anemia.

Cresp Injection encourages the production of red blood cells in the bone marrow. It regulates the hemoglobin in the blood. This injection is used in anemia in cancer patients receiving chemotherapy.

Side effects of Cresp Injection

There are Some major and minor side effects of this medicine. But not all side effects need doctor attention. If you may experience any side effects that become serious, You may consult your doctor.

Some of the common side effects of this medicine include

High blood pressure

Allergic reactions

Pain around  the injected area

Rash, redness on the skin

Blood clots 

Fluid retention 

How is Cresp Injection given?

Always take this medicine as per your doctor’s consultation. It is given in form of an injection by your doctor. Dose and duration will decide your doctor. Do not miss the dose. If you miss a dose skip the missed dose and follow your schedule regularly on the next day. Do not double the dose. Take medicine every day on time as prescribed by your doctor. Much other medicine can affect this, so let your doctor know all the medication you are using during the treatment.

How does Cresp Injection work?

Cresp Injection encourages the bone marrow to produce more red blood cells in the same way as the natural hormone erythropoietin.