Everolimus Tablets

What are Everolimus Tablets?

Everolimus is used with other medications such as (cyclosporine) to prevent rejection of a kidney transplant. It is used with other medications (such as tacrolimus) to prevent rejection of the liver transplant. It is sold under the brand name Afinitor, Votubia, and Zortress. It belongs to a class of drugs known as immunosuppressants. It works to weaken your body’s defense system ( immune system) to help your body accept the new organ as if it were it’s own.

What is Rejection?

Rejection is your body’s way of not accepting a kidney transplant. Although rejection is most common in the first six months after surgery. It can occur at any time. The transplant can usually recognize and treat a rejection before it causes any major or irreversible damage. It is very important to take medications according to the doctor’s prescription. 

What is Kidney Transplant Rejection?

A kidney transplant is a surgical procedure performed to replace a diseased kidney with a healthy kidney from another person. The kidney may come from a deceased organ donor or a living donor. Family members or individuals who are unrelated but make a good may be able to donate a portion of their kidney. This type of transplant is called a living donor kidney transplant

Rejection is a normal reaction of the body to a foreign object. When a new kidney is placed in a person’s body, the body sees the transplanted organ as a threat and tries to attack it. The immune system makes antibodies to try to kill the new organ, not realizing that the transplanted kidney is beneficial.

What is Liver transplant rejection?

A liver transplant is a surgical procedure performed to replace a diseased liver with a healthy liver from another person. The liver may come from a deceased organ donor or a living donor. Family members or individuals who are unrelated but make a good may be able to donate a portion of their liver. This type of transplant is called a living donor liver transplant.

Rejection is a normal reaction of the body to a foreign object. When a new liver is placed in a person’s body, the body sees the transplanted organ as a threat and tries to attack it. The immune system makes antibodies to try to kill the new organ, not realizing that the transplanted liver is beneficial.

Everolimus is taken to prevent transplant rejection. It is usually taken twice a day (every 12 hours) at the same time. Everolimus should be taken either always with food or always without food. Before taking medicine consult your doctor. Dose and duration will be decided by the necessity and need of the patient. It depends on the treatment and may change from time to time. You should take medicine as per your doctor’s advice. This medicine is strictly not recommended for children, pregnant women, and breastfeeding mothers. It takes some weeks and months to get a better result. Do not stop taking medicine before your doctor’s advice. 

The common side effects of this medicine include constipation, headache, nausea, and sores in the mouth/throat may occur. Some serious side effects include swelling hands/feet/ankles, wound problems, slow wound healing, the opening of the wound, decreased sexual ability, chest pain/pressure, shortness of breath, and unusual bleeding. Tell your doctor right away if any of these effects last or get worse, and tell your doctor or pharmacist promptly.

What are the benefits of the Everolimus Tablet?

• In the treatment of kidney and liver transplant rejection 

Everolimus is a Mechanistic target of rapamycin (mTOR) inhibitor that is also called an immunosuppressant. It works to prevent the action of mTOR, which plays a vital role in cell growth and proliferation. It can slow or stop the growth of certain cells and prevent tumors from growing their blood vessels. This medicine can also reduce the volume of lipomas and prevent the immune system from rejecting the transplanted organ.

Side effects of Everolimus

There are Some major and minor side effects of this medicine. But not all side effects need doctor’s attention. If you may experience any side effects that become serious, You may consult your doctor. Some of the common side effects of this medicine include:

• Diarrhea
• Constipation 
• Change in ability
• Weight loss
• Dry mouth
• Weakness
• Headache
• Nose bleed
• Dry skin
• Acne 
• Muscle cramps
• Hair loss
• Pain in arms, legs, or joints
• Anxiety
• Aggression

How Everolimus is taken?

Always take this medicine as per your doctor’s consultation. Everolimus is taken to prevent transplant rejection, It is usually taken twice a day (every 12 hours) at the same time. Everolimus should be taken either always with food or always without food. Dose and duration will decide your doctor. You are not allowed to crush, chew and break the medicine. Swallow it as a whole. Drink plenty of water. Do not miss the dose. If you miss a dose skip the missed dose and follow your schedule regularly on the next day. Do not double the dose. Take medicine every day on time as prescribed by your doctor. Much other medicine can affect this, so let your doctor know all the medication you are using during the treatment.

What is the work of Everolimus?

Everolimus is a class of medications called kinase inhibitors. It treats cancer by stopping cancer cells from reproducing and by decreasing the blood supply to the cancer cells. It prevents transplant rejection by decreasing the activity of the immune system.