What is Graftide S 360 Tablet?
Graftide S 360mg Tablet contains Mycophenolate Sodium as the active constituent. This medicine is indicated for patients who have undergone transplants that include the liver, kidney, or heart. This medication is given to avoid organ rejections. Rejections occur when our immune system identifies the new organ as a foreign body attacks it. This medicine is given in combination with other medicines such as corticosteroids and cyclosporine which also possess immunosuppressive action. Do not take medicine without any medical advice.
What is the use of Mycophenolate Sodium drug?
Mycophenolate sodium drug is sold under the brand name Myfortic. It is manufactured in India by Mylan Pharmaceuticals Private Limited. Mycophenolate sodium is the sodium salt form of mycophenolate acid. It is an immunosuppressant medicine used to prevent rejection following organ transplantation and to treat autoimmune conditions. It is used following kidney, liver, or heart transplantation. It can be given by mouth or by injection into a vein.
Mycophenolate acid exerts selective effects on the immune system in which it prevents the augmentation of T- cells, lymphocytes, and the formation of antibodies from B- cells. It may inhibit the leukocytes to reduce inflammation.
What is transplant rejection?
Rejection is a normal reaction of the body to a foreign object. When a new kidney is placed in a person’s body, the body sees the transplanted organ as a threat and tries to attack it. The immune system makes antibodies to try to kill the new organ, not realizing that the transplanted kidney is beneficial.
To prevent rejection, medication must be given for the rest of your life to fight rejection. Each person is an individual, and each transplant prefers different medications. The anti-rejection medications are most commonly used to treat the rejection process.
What is a kidney transplant?
Kidney transplantation is the start of a new lease on life. While most kidney transplants are successful, complications can occur such as kidney rejection. When a kidney is placed your body reacts as if it is a foreign body. Immunosuppressive medicines can help prevent your immune system from damaging your new kidney.
The kidneys are two bean-shaped organs located on each side of the spine just below the rib cage. Each is about the size of a fist. Their main function is to filter and remove waste, minerals, and fluid from the blood by producing urine.
- What are the requirements of a kidney transplant?
Each hospital has its criteria but in general, candidates should have:
End-stage renal failure an be on dialysis
Late-stage chronic kidney disease
A life expectancy of at least five years
A full understanding of postoperative instructions and care.
What is a Liver transplant?
The liver is the largest abdominal organ. The liver weighs about 1200 – 1500 grams on average roughly 2% of body weight. The liver as a whole has a hepatic artery supplying oxygenated blood, a portal vein carrying blood from the intestines to the liver, and bile ducts, draining bile formed in the liver to the intestines. Blood from the liver is delivered to the heart – via – three hepatic veins.
A liver transplant means removing a whole or part of the liver from a deceased living donor, and placing and attaching it to a patient after removing the whole or the diseased liver.
- What are the requirements of a liver transplant?
The minimum requirements for liver transplant are:
Signs of liver failure
Surgery and recovery
Risk of alcohol or drug abuse
What is a heart transplant?
A heart transplant is surgical transplantation that is performed on patients with end-stage heart failure or severe coronary artery disease. The patient’s heart is replaced with a donor’s healthy heart and is performed as a life-saving measure.
A heart transplant is the last option and is performed when other heart transplant treatments have failed. It is done in cases of severe heart failure.
- What are the requirements of a heart transplant?
Some causes of heart transplant include:
High blood pressure
Heart valve disease
Alcoholism or drugs abuse
Chronic lung disease
Low red blood cell count
Heart muscle is enlarged
The amount of Graftide S 360mg Tablet you take depends on the type of transplant you have. Follow your doctor’s instructions on this. You should take an empty stomach, at least 1 hour before or 2 hours after a meal. Before taking medicine consult your doctor. Dose and duration will be decided by the necessity and need of the patient. It depends on the treatment and may change from time to time. You should take medicine as per your doctor’s advice. This medicine is strictly not recommended for children, pregnant women, and breastfeeding mothers. It takes some weeks and months to get a better result. Do not stop taking the medicine before your doctor’s advice.
Common side effects of this medicine include nausea, stomach pain, diarrhea, headache, high blood pressure, change in white blood cells, and difficulty sleeping. It lowers your immune system so you are more prone to infections. if these side effects become serious. Your doctor can prevent and give you relief from the side effects during the treatment. It makes you feel better. Regular blood tests are required to check blood cells.
The benefit of Graftide S 360mg Tablet
- In the treatment of prevention of transplantation rejection
Graftide S 360mg belongs to a group of medicines known as immunosuppressive agents. It lowers your immune system and reduces the chance of your body attacking the transplanted organ. Organ rejection happens when your immune system treats the new organ as an invader and attacks it. This medicine may be used in combination with other medicines to suppress the immune response and help your body to accept the new organ.
Side effects of Graftide S 360mg Tablet
Here are Some major and minor side effects of this medicine. But not all side effects need a doctor’s attention. If you observe any side effects become serious, You may consult your doctor.
Some of the common side effects of this medicine include:
Nausea or vomiting
Loss of appetite
High blood pressure
Decreased white blood cell count
How is the Graftide S 360mg Tablet taken?
The amount of Graftide S 360mg Tablet you take depends on the type of transplant you have. Follow your doctor’s instructions on this. You should take an empty stomach, at least 1 hour before or 2 hours after a meal. Always take this medicine as per your doctor’s consultation. Dose and duration will decide your doctor. You are not allowed to crush, chew and break the medicine. Swallow it as a whole. Drink plenty of water. Do not miss the dose. If you miss a dose skip the missed dose and follow your schedule regularly on the next day. Do not double the dose. Take medicine every day on time as prescribed by your doctor. Much other medicine can affect this medicine so let your doctor know all medication you are using during the treatment.
How does the Graftide S 360mg Tablet work?
Graftide S 360mg Tablet is an enteric-coated tablet that will pass into the stomach and get dissolved in the intestine. This medicine belongs to the class of immunosuppressive agents that prevents the enzyme inosine monophosphate dehydrogenase which plays a significant role in purine synthesis. Therefore it affects the immune cells and impairs new organ transplantation.