Ibrunat Capsules

What are Ibrunat Capsules?

Ibrunat contains a drug called Ibrutinib. It belongs to a class of drugs known as kinase inhibitors. This medicine is used to treat Mantle cell lymphoma and blood cancer such as chronic lymphocytic leukemia. This medication is also used to treat chronic graft versus host disease, which is an immune system disorder. Lymphoma is a malignancy that affects the immune system cells, which are the body’s first line of defense against infection. Leukemia, on the other hand, is cancer that affects white blood cells. Lymphoma and leukemia come in a variety of forms. 

What Ibrutinib drug is used for?

Ibrutinib is sold under the brand name Imbruvica. This medication is used to treat mantle cell lymphoma ( a fast-growing cancer cell that begins in the cells of the immune system), chronic lymphocytic leukemia (a type of cancer that begins in the white blood cells ), and chronic graft versus host disease ( a complication of stem cell transplant in a procedure that replaces diseased bone marrow with healthy bone marrow that may start a while after the transplant and last for a long time). Ibrutinib is in a class of medications called kinase inhibitors. It works to block the action of the abnormal protein that signals cancer cells to multiply. This helps to stop the spread of cancer cells.

What is Mantle cell Lymphoma?

Mantle cell lymphoma is a rare blood cancer that starts in white blood cells in your lymph nodes. It helps your body to fight infections.

Lymphocytes are found in your lymph nodes, the pea-sized glands in your neck, groin, armpits, and other places that are the parts of your immune system. If you have mantle cell lymphoma, some of your lymphocytes, called “B- cell’ lymphocytes change into cancer cells. This means they multiply quickly and out of control.

These cancer cells start to form tumors in your lymph nodes. They may enter your blood or lymph channels and spread to other lymph nodes, as well as your bone marrow, digestive tract, spleen, and liver.

Mantle cell lymphoma has spread to other parts of the body. There is no cure for mantle cell lymphoma, but there are treatments that put the condition into suspension. Researchers are finding new treatments and new ways to use the treatment to make suspension periods last longer. 

• What are the signs and symptoms of Mantle cell lymphoma?

 Some symptoms of Mantle cell lymphoma include:

Nausea and vomiting 

Diarrhea

Swollen lymph nodes

Heartburn 

A sense of fullness

Pressure and pain in the lower back

Fatigue

What is Chronic lymphocytic leukemia?

Chronic lymphocytic leukemia (CLL) is a type of chronic leukemia. “ Chronic” means that leukemia usually gets worse slowly. In CLL, the bone marrow makes abnormal lymphocytes ( a type of white blood cell). When the abnormal cells are removed from the healthy cells, it can lead to infection, anemia, and easy bleeding. The abnormal cells can also spread outside the blood to other parts of the body. CLL is one of the most common types of leukemia in adults. It often occurs during or after middle age. It is rare in children. 

Some people never need treatment, but if you treat it, it slows the disease and eases symptoms. People who get medical treatment live longer today if they follow the doctor’s advice and take medicine timely.

• What are the signs and symptoms of Chronic lymphocytic leukemia?

You have had no symptoms for a while. Over time, you may have:

Swollen lymph nodes in your neck, armpits, stomach, or groin. 

Shortness of breath

Pain or fullness in your stomach

Fatigue

Night sweats

Fever and infections

Loss of appetite and weight

Ibrunat comes as a capsule and a tablet to take by mouth. It is usually taken once daily. Take this medicine at around the same time every day. Before taking medicine consult your doctor. Dose and duration will be decided by the necessity and need of the patient. It depends on the treatment and may change from time to time. You should take medicine as per your doctor’s advice. This medicine is strictly not recommended for children, pregnant women, and breastfeeding mothers. It takes some weeks and months to get a better result. Do not stop taking the medicine before your doctor’s advice.

The common side effects of this medicine include headache, diarrhea, and nausea. It may decrease the blood cells ( such as red and white blood cells) in your blood. It may increase the chance of infections in your body. Regular blood tests are essential to check blood cells in your body.

The benefit of Ibrunat Capsules

• In the treatment of Mantle cell lymphoma

This medicine is used to slow down or stop the growth of cancer cells. It works to weaken your body’s immune system. It belongs to a class of drugs known as kinase inhibitors. 

• In the treatment of Chronic lymphocytic leukemia

It is a type of cancer that begins in the white blood cells. Ibrunat capsules are in a class of medications called kinase inhibitors. It works to block the action of the abnormal protein that signals cancer cells to multiply. This medicine helps to stop the spread of cancer cells.

Side effects of Ibrunat Capsules

Here are Some major and minor side effects of this medicine. But not all side effects need a doctor’s attention. If you observe any side effects become serious, You may consult your doctor.

Some of the common side effects of this medicine include:

Upset stomach

Diarrhea

Decreased appetite

Headache

Joint and muscle pain

Numbness of arms, legs

Anxiety 

Tiredness

Constipation

Swelling of ankles, legs, or feet

How is the Ibrunat capsule taken?

Ibrunat comes as a capsule and a tablet to take by mouth. It is usually taken once daily. Take this medicine at around the same time every day. Always take this medicine as per your doctor’s consultation. Dose and duration will decide your doctor. You are not allowed to crush, chew and break the medicine. Swallow it as a whole. Drink plenty of water. Do not miss the dose. If you miss a dose skip the missed dose and follow your schedule regularly on the next day. Do not double the dose. Take medicine every day on time as prescribed by your doctor. Much other medicine can affect this medicine so let your doctor know all medication you are using during the treatment.

How Ibrunat capsule work?

This medicine is used to treat mantle cell lymphoma and chronic lymphocytic leukemia. It interferes with the growth of cancer cells, which are destroyed by the body. It is an antineoplastic agent ( a type of cancer medicine).