Myfortic 360mg Tablet

What is a Myfortic 360mg Tablet?

Myfortic 360mg Tablet contains a salt composition called Mycophenolate mofetil. It is an immunosuppressive medicine (a medicine that weakens the immune system). It is used in combination with other medications to prevent organ rejection ( when your body’s immune system treats the new organ as a foreign object and attacks it) after a kidney, liver, or heart transplant. This medicine works to suppress the immune system so the body does not reject the transplanted organ.

What Mycophenolate mofetil drug is used for?

Mycophenolate mofetil is sold under the brand name Cellcept. It is manufactured in India by Novartis India Limited. It is an immunosuppressant medicine. It is a medicine that contains the active substance Cellcept. It is available as capsules, tablets or powder to be made into an oral suspension and a powder to be made up into a solution for infusion into a vein. 

It is used to prevent the body from rejecting transplanted organs such as kidneys, liver, or heart. It is used with cyclosporine and corticosteroids (other medicines used to prevent organ rejection). This medicine is used with a prescription.

What is transplant rejection?

Rejection can occur at any time after your transplant, but it is more likely to happen within the first 6 months. Transplant rejection happens when your body does not accept the new organ. It can happen just after your surgery or in the years following your transplant. Through a treatment plan of immunosuppressive medication, the effects of rejection can be reversed and your body can readjust to your new organ.

What is a kidney transplant?

Kidney transplantation is the start of a new lease on life. While most kidney transplants are successful, complications can occur such as kidney rejection. When a kidney is placed your body reacts as if it is a foreign body. Immunosuppressive medicines can help prevent your immune system from damaging your new kidney. 

The kidneys are two bean-shaped organs located on each side of the spine just below the rib cage. Each is about the size of a fist. Their main function is to filter and remove waste, minerals, and fluid from the blood by producing urine. 

• What are the requirements of a kidney transplant?

Each hospital has its criteria but in general, candidates should have:

End-stage renal failure an be on dialysis

Late-stage chronic kidney disease

A life expectancy of at least five years

A full understanding of postoperative instructions and care.

What is a Liver transplant?

The liver is the largest abdominal organ. The liver weighs about 1200 – 1500 grams on average roughly 2% of body weight. The liver as a whole has a hepatic artery supplying oxygenated blood, a portal vein carrying blood from the intestines to the liver, and bile ducts, draining bile formed in the liver to the intestines. Blood from the liver is delivered to the heart – via – three hepatic veins.

A liver transplant means removing a whole or part of the liver from a deceased living donor, and placing and attaching it to a patient after removing the whole or the diseased liver.

• What are the requirements of a liver transplant?

The minimum requirements for liver transplant are:

Signs of liver failure

Surgery and recovery

Risk of alcohol or drug abuse

Liver cancer 

Cirrhosis

What is a heart transplant?

A heart transplant is surgical transplantation that is performed on patients with end-stage heart failure or severe coronary artery disease. The patient’s heart is replaced with a donor’s healthy heart and is performed as a life-saving measure.

A heart transplant is the last option and is performed when other heart transplant treatments have failed. It is done in cases of severe heart failure.

• What are the requirements of a heart transplant?

Some causes of heart transplant include:

Heart attack

Viral infection

High blood pressure

Heart valve disease

Irregular heartbeats

Heart defects

Alcoholism or drugs abuse

Chronic lung disease

Low red blood cell count

Heart muscle is enlarged

The amount of Myfortic 360mg Tablet you take depends on the type of transplant you have. You should take it on an empty stomach, at least one hour before or two hours after a meal. Before taking medicine consult your doctor. Dose and duration will be decided by the necessity and need of the patient. It depends on the treatment and may change from time to time. You should take medicine as per your doctor’s advice. This medicine is strictly not recommended for children, pregnant women, and breastfeeding mothers. It takes some weeks and months to get a better result. Do not stop taking the medicine before your doctor’s advice.

Common side effects of this medicine include nausea, stomach pain, diarrhea, headache, high blood pressure, change in white blood cells, and difficulty sleeping. It lowers your immune system so you are more prone to infections. if these side effects become serious. Your doctor can prevent and give you relief from the side effects during the treatment. It makes you feel better. Regular blood tests are required to check blood cells.

The benefit of Myfortic 360mg Tablet

• In the treatment of prevention of transplantation rejection

Myfortic 360mg Tablet is effective in preventing the rejection of transplanted kidneys after six months. In children undergoing the risk of organ rejection. kidney transplants, the rejection rates were similar to those seen in adults. Taking Myfortic lowers the risks of organ rejections.

In heart transplants, around 38% of adult patients taking Mycortic lower the risk of rejection after six months. Following a liver transplant, 38% of the adult patients taking Mycept had rejected their new liver after six months. But the proportion of patients was lower in comparison to other medicines.

Side effects of Myfortic 360mg Tablet

Here are Some major and minor side effects of this medicine. But not all side effects need a doctor’s attention. If you observe any side effects become serious, You may consult your doctor.

Some of the common side effects of this medicine include:

Headache

Diarrhea

Dizziness

Nausea or vomiting

Swelling of feet or lower legs

Trouble with sleeping

Uncontrolled shaking of arms or legs 

Difficulty in breathing

Chest pain

Black or tarry stools

Yellowing of skin and eyes

Drowsiness

How is the Myfortic 360mg Tablet taken?

The amount of Myfortic 360mg Tablet you take depends on the type of transplant you have. You should take it on an empty stomach, at least one hour before or two hours after a meal. Always take this medicine as per your doctor’s consultation. Dose and duration will decide your doctor. You are not allowed to crush, chew and break the medicine. Swallow it as a whole. Drink plenty of water. Do not miss the dose. If you miss a dose skip the missed dose and follow your schedule regularly on the next day. Do not double the dose. Take medicine every day on time as prescribed by your doctor. Much other medicine can affect this medicine so let your doctor know all medication you are using during the treatment.

How does the Myfortic 360mg Tablet work?

Mycept 360mg Tablet contains active substances, mycophenolate mofetil. It is an immunosuppressive medicine, which blocks an enzyme called “inosine monophosphate dehydrogenase”. This enzyme is important for the formation of DNA in cells, particularly in the lymphocytes (a type of white blood cell which is involved in the rejection of organ transplants). By preventing the production of new DNA, myfortic reduces the rate at which the lymphocytes multiply. This makes them less effective at recognizing and attacking the transplanted organ, lowering the risk of the organ being rejected.