Nitib 140 mg Capsule

What is Nitib 140 mg Capsule?

Nitib 140 mg Capsule contains a salt called Ibrutinib. It is used to treat chronic lymphocytic leukemia, and mantle cell lymphoma. These are cancers of the white blood cells called lymphocytes that are part of the immune system. And graft vs host disease. It works to inhibit the abnormal protein that helps the cancer cells to multiply. This medicine is not recommended for children.

What Ibrutinib drug is used for?

Ibrutinib is sold under the brand name Imbruvica. It is manufactured by Hetero Healthcare Limited. This medication is used to treat mantle cell lymphoma ( a fast-growing cancer cell that begins in the cells of the immune system), chronic lymphocytic leukemia (a type of cancer that begins in the white blood cells ), and chronic graft versus host disease ( a complication of stem cell transplant in a procedure that replaces diseased bone marrow with healthy bone marrow that may start a while after the transplant and last for a long time). Ibrutinib is in a class of medications called kinase inhibitors. It works to block the action of the abnormal protein that signals cancer cells to multiply. This helps to stop the spread of cancer cells.

What is Mantle cell lymphoma?

Mantle cell lymphoma is a rare blood cancer that starts in white blood cells in your lymph nodes. This type of cancer grows slowly before starting to grow more rapidly. Mantle cell lymphoma quickly spreads throughout your lymphatic system and to other parts of the body. 

Lymphocytes are found in your lymph nodes, the pea-sized glands in your neck, groin, armpits, and other places that are part of the immune system. In mantle cell lymphoma, some of your lymphocytes called “B– cell” lymphocytes, change into cancer cells. This means they multiply quickly and out of control.

There is no cure for mantle cell lymphoma, but there are treatments that put the conditions into cancellation. It means you don’t have symptoms and tests show no signs of cancer.

• What are the signs and symptoms of Mantle cell lymphoma?

 Some symptoms of Mantle cell lymphoma include:

Nausea and vomiting 

Diarrhea

Swollen lymph nodes

Heartburn 

A sense of fullness

Pressure and pain in the lower back

Fatigue

What is Chronic lymphocytic leukemia?

Chronic lymphocytic leukemia (CLL) is a cancer of a type of white blood cell called lymphocytes. These cells are found in the bone marrow and other parts of the body. Bone marrow is the soft tissue in the center of bones that helps form all blood cells.

CLL causes a slow increase in a certain type of white blood cells called B- lymphocytes or B cells. Cancer cells spread through the blood and bone marrow. CLL also affects the lymph nodes or other organs such as the liver and spleen. CLL eventually can cause the bone marrow to lose its function. 

• What are the signs and symptoms of Chronic lymphocytic leukemia?

You have had no symptoms for a while. Over time, you may have:

Swollen lymph nodes in your neck, armpits, stomach, or groin. 

Shortness of breath

Pain or fullness in your stomach

Fatigue

Night sweats

Fever and infections

Loss of appetite and weight

Nitib 140 mg is available in the form of oral capsules and oral tablets as well. It is prescribed to take it once a day at the same time every day. Before taking medicine consult your doctor. Dose and duration will be decided by the necessity and need of the patient. It depends on the treatment and may change from time to time. You should take medicine as per your doctor’s advice. This medicine is strictly not recommended for children, pregnant women, and breastfeeding mothers. It takes some weeks and months to get a better result. Do not stop taking the medicine before your doctor’s advice.

The most common side effects of this medicine include fatigue, headache, nausea, insomnia, and anemia. Inform your doctor if these side effects become serious. Your doctor can prevent and give you relief from the side effects during the treatment. It makes you feel better. It reduces your blood cells ( red and white blood cells). It increases the chances of infections. Regular blood tests are required to check blood cells in your body.

The benefit of Nitib 140 mg Capsule

• In the treatment of Mantle cell lymphoma

This capsule contains Ibrutinib which is an antineoplastic, tyrosine kinase inhibitor. It produces its action by acting on tyrosine present on the B- cell antigen receptor and cytokine receptor. Nitib 140 mg inhibits tyrosine kinase present in receptors which gives the signaling process required for angiogenesis and the production of abnormal cells is inhibited. It reduces the abnormal cells and minimizes and treats and controls.

• In the treatment of Chronic lymphocytic leukemia

Nitib 140 mg helps to block the protein called tyrosine kinase that helps these cancer cells grow and survive. It stops the growth and worsening of cancer. It prevents the multiplication and spreading of cancer cells.

Side effects of Nitib 140 mg Capsule

Here are Some major and minor side effects of this medicine. But not all side effects need a doctor’s attention. If you observe any side effects become serious, You may consult your doctor.

Some of the common side effects of this medicine include:

Blood in stools 

Blood in vomiting

Cough up blood

Dizziness

Weakness

Severe headache

Serious infections 

Decreased blood counts 

Hypertension

Affect heart rate

How is Nitib 140 mg capsule taken?

Nitib 140 mg is available in the form of oral capsules and oral tablets as well. It is prescribed to take it once a day at the same time every day. Always take this medicine as per your doctor’s consultation. Dose and duration will decide your doctor. You are not allowed to crush, chew and break the medicine. Swallow it as a whole. Drink plenty of water. Do not miss the dose. If you miss a dose skip the missed dose and follow your schedule regularly on the next day. Do not double the dose. Take medicine every day on time as prescribed by your doctor. Much other medicine can affect this medicine so let your doctor know all medication you are using during the treatment.

How does the Nitib 140 mg capsule work?

Nitib 140 mg is an antineoplastic tyrosine kinase inhibitor. It produces its action by inhibiting tyrosine present on the B cell antigen receptor and the signaling process for angiogenesis and production of abnormal cells is inhibited. It minimizes the growth of abnormal cancer cells and removes the metastasis of tumors or cancers.