Tacrograf 2mg Capsule

What is a Tacrograf 2 mg Capsule?

 Tacrograf 2 mg Capsule contains a drug called Tacrolimus. It belongs to the group of medicines known as Immunosuppressants. It is used with other medications to prevent your body from rejecting a new organ such as a liver, kidney, or heart after a transplant. It does so by weakening your body’s immune system so it does not attack the new organ. 

What Tacrolimus drug is used for?

Tacrolimus is sold under the brand name Prograf. It is manufactured in India by Biocon Limited. Tacrolimus is used along with other medications to prevent rejection ( attack of a transplanted organ by the immune system of a person receiving the organ) in people who have a kidney transplant. It is used along with other medicines to prevent rejection in people who have received a liver or heart transplant. It is in a class of medications called immunosuppressants. It works to decrease the activity of the immune system to prevent it from attacking the transplanted organ.

What is transplant rejection?

Rejection is a very fearful word, but it doesn’t always mean you are losing your transplanted organ. Rejection is when the organ recipient’s immune system recognizes the donor organ as foreign and attempts to eliminate it. It occurs when your immune system detects things like bacteria or a virus. Rejection occurs with every transplant. 

Despite the use of immunosuppressant therapy, acute rejection can occur and often lead to chronic rejection. Chronic rejection is characterized by gradual loss of organ function. It can occur weeks, months, or years after transplantation. 

What is a Kidney transplant?

A kidney transplant, sometimes known as a renal transplant, is a treatment for kidney failure at end-stage renal disease. Kidney transplant surgery is a major failure during which a person with kidney failure receives a new kidney either from a living donor or a deceased donor. A successful kidney transplant is the closest to natural kidney function and is considered the most effective treatment for a kidney transplant. It offers a chance for a longer and healthier life.

• What are the requirements of a kidney transplant?

Each hospital has its criteria but in general, candidates should have:

End-stage renal failure an be on dialysis

Late-stage chronic kidney disease

A life expectancy of at least five years

A full understanding of postoperative instructions and care.

What is a Liver transplant?

The liver is a vital organ, meaning that one cannot live without it. The liver serves many critical functions including metabolism of drugs and toxins, removing degradation products of normal body metabolism, and synthesis of many important proteins and enzymes. 

A liver transplant is an operation that replaces a patient’s diseased liver with a whole or partial healthy liver from another person. Transplantation is the only cure for insufficiency or liver failure because no device or machine performs all the functions of the liver. 

• What are the requirements of a liver transplant?

The minimum requirements for liver transplant are:

Signs of liver failure

Surgery and recovery

Risk of alcohol or drug abuse

Liver cancer 

Cirrhosis

What is a heart transplant?

A heart transplant is a surgery to remove the diseased heart from a person and replace it with a healthy one from an organ donor. To remove the heart from the donor, two or more healthcare providers must declare the donor brain dead. 

You may need a heart transplant if you have end-stage heart failure, a disease in which the heart muscle is failing severely in its attempt to pump blood through the body. It means other treatments are no longer working. End-stage heart failure is the final stage of heart failure.

• What are the requirements of a heart transplant?

Some causes of heart transplant include:

Heart attack

Viral infection

High blood pressure

Heart valve disease

Irregular heartbeats

Heart defects

Alcoholism or drugs abuse

Chronic lung disease

Low red blood cell count

Heart muscle is enlarged

The benefit of Tacrograf 2 mg Capsule

• In the treatment of prevention of transplantation rejection

Tacrograf 2 mg Capsule belongs to a class of drugs known as immunosuppressants and is used to prevent organ rejection in transplant recipients. When your immune system sees a new organ as an intruder and attacks it. It is called organ rejection. This medication minimizes the likelihood of your body attacking the donated organ by weakening your immune response. It is used in combination with other medicines to increase your chances of a successful transplant. 

Side effects of Tacrograf 2 mg Capsule

Here are Some major and minor side effects of this medicine. But not all side effects need a doctor’s attention. If you observe any side effects become serious, You may consult your doctor.

Some of the common side effects of this medicine include:

Headache

Diarrhea

Dizziness

Nausea or vomiting

Swelling of feet or lower legs

Blurred vision

Sweating

Weight loss 

Back pain

Joint pain

Scaly skin

Loss of appetite

How is the Tacrograf 2 mg Capsule taken?

Take a Tacrograf 2 mg capsule either with or without food. Always take this medicine as per your doctor’s consultation. Dose and duration will decide your doctor. You are not allowed to crush, chew and break the medicine. Swallow it as a whole. Drink plenty of water. Do not miss the dose. If you miss a dose skip the missed dose and follow your schedule regularly on the next day. Do not double the dose. Take medicine every day on time as prescribed by your doctor. Much other medicine can affect this medicine so let your doctor know all medication you are using during the treatment.

How does the Tacrograf 2 mg Capsule work?

This medicine works to obstruct the action of Calcineurin, a substance found in the white blood cells known as T- lymphocytes. This prevents the T- lymphocytes from producing lymphokines, in case of a foreign particle is detected in the body.