What is Takfa 0.25 mg Capsule?
Takfa 0.25 mg capsule is an immunosuppressant medicine. It belongs to the group of medicines called Tacrolimus. It helps to prevent organ rejection in people who have had liver, heart, or kidney transplants. Following an organ transplant, our body’s immune system will try to reject the new organ. This medication controls the body’s immune response to accept the transplanted organ.
What Tacrolimus drug is used for?
Tacrolimus is sold under the brand name Prograf. It is manufactured in India by Intas Pharmaceuticals Limited. Tacrolimus is used along with other medications to prevent rejection ( attack of a transplanted organ by the immune system of a person receiving the organ) in people who have a kidney transplant. It is used along with other medicines to prevent rejection in people who have received a liver or heart transplant. It is in a class of medications called immunosuppressants. It works to decrease the activity of the immune system to prevent it from attacking the transplanted organ.
What is transplant rejection?
Rejection is a very fearful word, but it doesn’t always mean you are losing your transplanted organ. Rejection is when the organ recipient’s immune system recognizes the donor organ as foreign and attempts to eliminate it. It occurs when your immune system detects things like bacteria or a virus. Rejection occurs with every transplant.
Despite the use of immunosuppressant therapy, acute rejection can occur and often lead to chronic rejection. Chronic rejection is characterized by gradual loss of organ function. It can occur weeks, months, or years after transplantation.
What is a kidney transplant?
Kidney transplantation is the start of a new lease on life. While most kidney transplants are successful, complications can occur such as kidney rejection. When a kidney is placed your body reacts as if it is a foreign body. Immunosuppressive medicines can help prevent your immune system from damaging your new kidney.
The kidneys are two bean-shaped organs located on each side of the spine just below the rib cage. Each is about the size of a fist. Their main function is to filter and remove waste, minerals, and fluid from the blood by producing urine.
- What are the requirements of a kidney transplant?
Each hospital has its criteria but in general, candidates should have:
End-stage renal failure an be on dialysis
Late-stage chronic kidney disease
A life expectancy of at least five years
A full understanding of postoperative instructions and care.
What is a Liver transplant?
The liver is the largest abdominal organ. The liver weighs about 1200 – 1500 grams on average roughly 2% of body weight. The liver as a whole has a hepatic artery supplying oxygenated blood, a portal vein carrying blood from the intestines to the liver, and bile ducts, draining bile formed in the liver to the intestines. Blood from the liver is delivered to the heart – via – three hepatic veins.
A liver transplant means removing a whole or part of the liver from a deceased living donor, and placing and attaching it to a patient after removing the whole or the diseased liver.
- What are the requirements of a liver transplant?
The minimum requirements for liver transplant are:
Signs of liver failure
Surgery and recovery
Risk of alcohol or drug abuse
What is a heart transplant?
A heart transplant is surgical transplantation that is performed on patients with end-stage heart failure or severe coronary artery disease. The patient’s heart is replaced with a donor’s healthy heart and is performed as a life-saving measure.
A heart transplant is the last option and is performed when other heart transplant treatments have failed. It is done in cases of severe heart failure.
- What are the requirements of a heart transplant?
Some causes of heart transplant include:
High blood pressure
Heart valve disease
Alcoholism or drugs abuse
Chronic lung disease
Low red blood cell count
Heart muscle is enlarged
Take a Takfa 0.25 mg capsule at least 2 to 3 hours after a meal. You should take it on an empty stomach to get the most benefit. Before taking medicine consult your doctor. Dose and duration will be decided by the necessity and need of the patient. It depends on the treatment and may change from time to time. You should take medicine as per your doctor’s advice. This medicine is strictly not recommended for children, pregnant women, and breastfeeding mothers. It takes some weeks and months to get a better result. Do not stop taking the medicine before your doctor’s advice.
Common side effects of this medicine include nausea, stomach pain, diarrhea, and difficulty sleeping. It lowers your immune system so you are more prone to infections. if these side effects become serious. Your doctor can prevent and give you relief from the side effects during the treatment. It makes you feel better.
The benefit of Takfa 0.25 mg Capsule
- In the treatment of prevention of transplantation rejection
Takfa 0.25 mg capsule belongs to a group of medicines known as immunosuppressants. Organ rejection happens when your immune system treats the new organ as an occupier and attacks it. This medicine weakens your immune system and reduces the chance of your body attacking the transplanted organ. It is used in combination with other medicines to make it much more likely that your transplant operation will be successful.
Side effects of Takfa 0.25 Capsule
Here are Some major and minor side effects of this medicine. But not all side effects need a doctor’s attention. If you observe any side effects become serious, You may consult your doctor.
Some of the common side effects of this medicine include:
Nausea or vomiting
Swelling of feet or lower legs
Loss of appetite
How is the Takfa 0.25 mg Capsule taken?
Take a Takfa 0.25 mg capsule at least 2 to 3 hours after a meal. You should take it on an empty stomach to get the most benefit. Always take this medicine as per your doctor’s consultation. Dose and duration will decide your doctor. You are not allowed to crush, chew and break the medicine. Swallow it as a whole. Drink plenty of water. Do not miss the dose. If you miss a dose skip the missed dose and follow your schedule regularly on the next day. Do not double the dose. Take medicine every day on time as prescribed by your doctor. Much other medicine can affect this medicine so let your doctor know all medication you are using during the treatment.
How does a Takfa 0.25 mg Capsule work?
This capsule is an immunosuppressant. It works to suppress your body’s immune response following the transplant of an organ such as liver, heart, or kidney failure. This helps your body to accept the new organ as if it were your own.