Takfa 0.5 mg Capsule

What is Takfa 0.5 mg Capsule?

Takfa 0.5mg capsule contains a drug called Tacrolimus. It belongs to the group of medicines called Immunosuppressants. It is used to prevent your body from rejecting a new organ ( such as a liver, heart, or kidney) after a transplant. So it weakens your body’s immune system so that the new organ is not attacked. This medication controls the body’s immune system to accept the transplanted organ.

What Tacrolimus drug is used for?

Tacrolimus is sold under the brand name Prograf. It is manufactured in India by Intas Pharmaceuticals Ltd. Tacrolimus is used along with other medications to prevent rejection ( attack of a transplanted organ by the immune system of a person receiving the organ) in people who have a kidney transplant. It is used along with other medicines to prevent rejection in people who have received a liver or heart transplant. It is in a class of medications called immunosuppressants. It works to decrease the activity of the immune system to prevent it from attacking the transplanted organ.

What is transplant rejection?

Each person is a one-of-a-kind collection of cells, tissues, and organs. The body system that recognizes a person’s cells and tissues are called the immune system. Rejection is a process in which the immune system finds foreign cells and tissues in the body. It attempts to destroy them to protect the body from harm,

When a person receives a kidney transplant, the immune system sees it as foreign and attempts to reject it by producing cells and or antibodies that occupy and damage the kidney. To prevent the immune system from damaging the transplanted kidney, you will take immunosuppressant ( anti-rejection ) drugs. It is very important to take your medications every day, as prescribed by your doctor. A sudden decline in kidney transplant functions due to injury caused by the immune system can occur despite taking these medications. These events are called “ rejections”.

What is a Kidney transplant?

The normal function of the kidney involves two kidney bean-shaped organs that produce urine. Urine is carried to the bladder by the way of the bladder. The bladder serves as a storehouse for urine. When the body senses that the bladder is full, the urine is excreted from the bladder through the urethra.

When the kidney stops working, renal failure occurs. If renal failure continues, end-stage renal disease results in the accumulation of toxic waste products in the body, In this case, either dialysis or transplantation is required. In this kidney transplant, patients receive a new kidney from a deceased donor or living donor. A transplant offers to live a normal life. However, It also involves a life-long dependence on drugs to keep the new kidney healthy. 

• What are the requirements of a kidney transplant?

Each hospital has its criteria but in general, candidates should have:

End-stage renal failure an be on dialysis

Late-stage chronic kidney disease

A life expectancy of at least five years

A full understanding of postoperative instructions and care.

What is a Liver transplant?

The liver is the largest organ in the body. It is located in the upper right portion of the abdomen, on the top of the stomach. Its main functions include processing proteins, fats, and carbohydrates, breaking down toxic substances, making chemical components, and secreting a yellow digestive juice called bile. 

A liver transplant is an operation to remove a diseased or damaged liver and replace it with a healthy one. It is usually recommended when the liver has been damaged to the point that it cannot perform its normal functions. This is known as liver failure or end-stage liver disease.

The liver can become gradually damaged as a result of illness, infection, or alcohol. This damage causes the liver to become scarred which is known as cirrhosis. Liver failure can also occur very rapidly as a result of inflammation and death of the liver tissue.

• What are the requirements of a liver transplant?

The minimum requirements for liver transplant are:

Signs of liver failure

Surgery and recovery

Risk of alcohol or drug abuse

Liver cancer 

Cirrhosis

What is a heart transplant?

Heart transplant surgery might be considered if you have severe heart failure. This means your heart isn’t pumping as much blood and oxygen around your body as it should be. If your condition is serious and other treatments aren’t helping, your cardiologist might send you for a transplant assessment.

Donor hearts can come from anywhere in the world. The amount of time between removing the heart from the donor and transplanting it into you. The quality of the heart, size, and how well it matches your blood and tissue type will be carefully considered.

• What are the requirements of a heart transplant?

Some causes of heart transplant include:

Heart attack

Viral infection

High blood pressure

Heart valve disease

Irregular heartbeats

Heart defects

Alcoholism or drugs abuse

Chronic lung disease

Low red blood cell count

Heart muscle is enlarged

Take a Takfa 0.5 mg capsule at least an hour before or two hours after a meal. You should take it on an empty stomach to get the most benefit. Before taking medicine consult your doctor. Dose and duration will be decided by the necessity and need of the patient. It depends on the treatment and may change from time to time. You should take medicine as per your doctor’s advice. This medicine is strictly not recommended for children, pregnant women, and breastfeeding mothers. It takes some weeks and months to get a better result. Do not stop taking the medicine before your doctor’s advice.

Common side effects of this medicine include nausea, stomach pain, diarrhea, and difficulty sleeping. It lowers your immune system so you are more prone to infections. if these side effects become serious. Your doctor can prevent and give you relief from the side effects during the treatment. It makes you feel better.

The benefit of Takfa 0.5 mg Capsule

• In the treatment of prevention of transplantation rejection

Takfa 0.5 mg capsule belongs to a group of medicines known as immunosuppressants. Organ rejection happens when your immune system treats the new organ as an occupier and attacks it. This medicine weakens your immune system and reduces the chance of your body attacking the transplanted organ. It is used in combination with other medicines to make it much more likely that your transplant operation will be successful.

Side effects of  Takfa 0.5 mg Capsule

Here are Some major and minor side effects of this medicine. But not all side effects need a doctor’s attention. If you observe any side effects become serious, You may consult your doctor.

Some of the common side effects of this medicine include:

Headache

Diarrhea

Dizziness

Nausea or vomiting

Swelling of feet or lower legs

Blurred vision

Sweating

Weight loss 

Back pain

Joint pain

Scaly skin

Loss of appetite

How is the Takfa 0.5 mg Capsule taken?

Take a Takfa 0.5 mg capsule at least an hour before or two hours after a meal. You should take it on an empty stomach to get the most benefit. Always take this medicine as per your doctor’s consultation. Dose and duration will decide your doctor. You are not allowed to crush, chew and break the medicine. Swallow it as a whole. Drink plenty of water. Do not miss the dose. If you miss a dose skip the missed dose and follow your schedule regularly on the next day. Do not double the dose. Take medicine every day on time as prescribed by your doctor. Much other medicine can affect this medicine so let your doctor know all medication you are using during the treatment.

How does the Takfa 0.5 mg Capsule work?

This capsule is an immunosuppressant drug. Your immune system is suppressed following an organ transplant with this medication such as liver, kidney, or heart. This allows your body to accept the new organ as if it were an integral part of you.