What are Temirazer Tablets?
Temirazer is a combination of drugs Tenofovir disoproxil fumarate 300 mg and Emtricitabine 200 mg. It is a fixed-dose combination (FDC) drug used for managing patients with HIV-1 infection and HIV-1 Pre-Exposure Prophylaxis. It is an antiviral medicine. It is a nucleotide reverse transcriptase inhibitor. This tablet acts on HIV reverse transcriptase enzyme. It interferes with their reproduction cycle. It is utilized in combination with other antiretroviral agents in adults and children weighing greater than 25 kgs.
What Tenofovir disoproxil fumarate and Emtricitabine drugs are used for?
Tenofovir disoproxil fumarate
Tenofovir disoproxil fumarate drug sold under the brand name Viread. It is manufactured in India by Aprazer Healthcare Private Limited. Tenofovir is used with other HIV medications to help control HIV infection. It helps to decrease the amount of HIV in your body so your immune system can work better. This lowers the chances of getting HIV complications and improves your quality of life. Tenofovir belongs to a class of drugs known as nucleotide reverse transcriptase inhibitors. Tenofovir is not a cure for HIV infection. You can decrease the risk of spreading HIV disease to others, and continue to take all the HIV medications exactly as prescribed by your doctor.
Emtricitabine is sold under the brand name Emtriva. This medicine is used along with other medications to treat HIV in adults and children who weigh at least 37 pounds (17 kgs). Emtricitabine is also used along with practicing safer sex to reduce the risk of HIV infection. This infection is high- risky in adults and teenagers who weigh at least 77 pounds ( 35 kgs). It is in a class of medications called nucleoside and nucleotide reverse transcriptase inhibitors. It works to slow the spread of HIV in the body. It will not cure HIV, but it may decrease your chance of developing acquired immunodeficiency syndrome (AIDS) and its related illness.
What is HIV?
HIV stands for human immunodeficiency virus. It harms your immune system by destroying a type of white blood cell that helps your body infection. This puts you at risk for serious infections and certain cancers.
- How does HIV spread?
HIV can spread in different ways:
- Through unprotected sex with a person with HIV. This is the most common way that it spreads.
- By sharing drug needles
- Through contact with the blood of a person with HIV
- From mother to baby during pregnancy, childbirth, or breastfeeding.
- What are the signs and symptoms of HIV infection?
The first signs of HIV infection may be flu-like symptoms:
Swollen lymph nodes
These symptoms may come and go within two or four weeks. This stage is called acute HIV infection.
Based on the body weight and age of the patients, this medicine’s recommended dosage is 1 tablet ( tenofovir disoproxil fumarate 300 mg + emtricitabine 200 mg) which is taken orally with or without food. For adults, 1 dose once daily is recommended. For children over 12 years of age and weight greater than 35 kgs, the same dose is given. Before taking medicine consult your doctor. Dose and duration will be decided by the necessity and need of the patient. It depends on the treatment and may change from time to time. You should take medicine as per your doctor’s advice. This medicine is strictly not recommended for children, pregnant women, and breastfeeding mothers. It takes some weeks and months to get a better result. Do not stop taking the medicine before your doctor’s advice.
Common side effects of this medicine include diarrhea, nausea, vomiting, fatigue, headache, dizziness, depression, insomnia, abnormal dreams, and rash. If these side effects become serious, you should consult your doctor. Your doctor can prevent and give you relief from the side effects. It makes you feel better during the treatment.
Benefits of Temirazer Tablets
- In the treatment of HIV- 1 infection
This medicine is used with other anti- HIV medications to help control HIV infection. This tablet helps to decrease the amount of HIV in your body and your immunity works better by reducing your chance of getting HIV complications like co-infections and other cancers. Temirazer tablets are not a cure for HIV infections but it improves immunity. This medicine is safely used in adolescence above 35 kgs of weight. It is used as a pre-prophylactic to exposure to a negative HIV test.
Side effects of Temirazer Tablets
Here are Some major and minor side effects of this medicine. But not all side effects need a doctor’s attention. If you observe any side effects become serious, You may consult your doctor.
Some of the common side effects of this medicine include:
Difficulty in sleeping
Rashes on the skin
How are Temirazer Tablets taken?
Based on the body weight and age of the patients, this medicine’s recommended dosage is 1 tablet ( tenofovir disoproxil fumarate 300 mg + emtricitabine 200 mg) which is taken orally with or without food. For adults, 1 dose once daily is recommended. For children over 12 years of age and weight greater than 35 kgs, the same dose is given. Always take this medicine as per your doctor’s consultation. Dose and duration will decide your doctor. You are not allowed to crush, chew and break the medicine. Swallow it as a whole. Drink plenty of water. Do not miss the dose. If you miss a dose skip the missed dose and follow your schedule regularly on the next day. Do not double the dose. Take medicine every day on time as prescribed by your doctor. Much other medicine can affect this medicine so let your doctor know all medication you are using during the treatment.
How do Temirazer Tablets work?
This tablet incorporates itself into a DNA strand and the reproduction process of viral particles is terminated. The active HIV molecule becomes inactive and further reproduction and multiplication process is stopped.