Thalidomide Uses Thalidomide is used in the treatment of multiple myeloma and lepra reaction. How Thalidomide works Thalidomide modulates the activity of body's immune system and helps indirectly attacking the cancer cells. It also stops the growth of blood vessels in cancer. Common side effects of Thalidomide Nausea, Rash, Breathlessness, Dizziness, Edema (swelling), Decreased calcium level in blood, Fatigue, Muscle weakness, Anxiety, Confusion, Decreased white blood cell count (neutrophils), Constipation, Tremors, Sensory neuropathy, Change in body weight, Decreased white blood cell count (lymphocytes), Thromboembolism, Muscle pain, Anaphylactic reaction, Headache, Sleepiness, Decreased potassium level in blood Disclaimer: The content on this website is only for informational purposes. Please take advice from your doctor or healthcare professionals. Do not self-medicate. Consult with your doctor before taking this medicine.