Vingraf 0.5mg Capsule

What is the Vingraf 0.5mg Capsule?

Vingraf 0.5mg contains a salt composition called Tacrolimus. This capsule is an immunosuppressant medicine. It helps to prevent organ rejection in people who have had liver, heart, or kidney transplants. Following an organ transplant, our body’s immune system will try to reject the new organ. This medication controls the body’s immune response to accept the transplanted organ.

What Tacrolimus drug is used for?

Tacrolimus is sold under the brand name Prograf. It is manufactured in India by Emcure Pharmaceuticals Limited. Tacrolimus is used along with other medications to prevent rejection (attack of a transplanted organ by the immune system of a person receiving the organ) in people who have a kidney transplant. It is used along with other medicines to prevent rejection in people who have received a liver or heart transplant. It is in a class of medications called immunosuppressants. It works to decrease the activity of the immune system to prevent it from attacking the transplanted organ.

What is transplant rejection?

Each person is a one-of-a-kind collection of cells, tissues, and organs. The body system that recognizes a person’s cells and tissues are called the immune system. Rejection is a process in which the immune system finds foreign cells and tissues in the body. It attempts to destroy them to protect the body from harm,

When a person receives a kidney transplant, the immune system sees it as foreign and attempts to reject it by producing cells and or antibodies that occupy and damage the kidney. To prevent the immune system from damaging the transplanted kidney, you will take immunosuppressant ( anti-rejection ) drugs. It is very important to take your medications every day, as prescribed by your doctor. A sudden decline in kidney transplant functions due to injury caused by the immune system can occur despite taking these medications. These events are called “ rejections”.

What is Kidney transplantation?

A kidney transplant is the transfer of a healthy kidney from one person into the body of a person who has little or no kidney function. The loss of kidney function known as end-stage chronic kidney disease or kidney failure is the most common reason for needing a kidney transplant. 

The main role of the kidneys is to filter waste products from the blood and convert them to waste. If the kidneys lose this ability, waste products build-up, which is life-threatening.

• What are the requirements of a kidney transplant?

Each hospital has its criteria but in general, candidates should have:

End-stage renal failure an be on dialysis

Late-stage chronic kidney disease

A life expectancy of at least five years

A full understanding of postoperative instructions and care.

What is a Liver transplant?

The liver is the largest organ in the body. It is located in the upper right portion of the abdomen, on the top of the stomach. Its main functions include processing proteins, fats, and carbohydrates, breaking down toxic substances, making chemical components, and secreting a yellow digestive juice called bile. 

Liver transplantation can be performed using a portion of the liver taken from either a deceased or a living donor. After a living donor liver transplant, both the donor’s remaining liver lobe and the transplanted lobe grow to full size. 

• What are the requirements of a liver transplant?

The minimum requirements for liver transplant are:

Signs of liver failure

Surgery and recovery

Risk of alcohol or drug abuse

Liver cancer 

Cirrhosis

What is a heart transplant?

A heart transplant is surgical transplantation that is performed on patients with end-stage heart failure or severe coronary artery disease. The patient’s heart is replaced with a donor’s healthy heart and is performed as a life-saving measure.

A heart transplant is the last option and is performed when other heart transplant treatments have failed. It is done in cases of severe heart failure.

• What are the requirements of a heart transplant?

Some causes of heart transplant include:

Heart attack

Viral infection

High blood pressure

Heart valve disease

Irregular heartbeats

Heart defects

Alcoholism or drugs abuse

Chronic lung disease

Low red blood cell count

Heart muscle is enlarged

Taking a Vingraf 0.5mg Capsule should take at least an hour before or two hours after a meal. You should take it on an empty stomach to get the most benefit. Take this medicine at around the same time every day. Before taking medicine consult your doctor. Dose and duration will be decided by the necessity and need of the patient. It depends on the treatment and may change from time to time. You should take medicine as per your doctor’s advice. This medicine is strictly not recommended for children, pregnant women, and breastfeeding mothers. It takes some weeks and months to get a better result. Do not stop taking the medicine before your doctor’s advice.

Common side effects of this medicine include nausea, stomach pain, diarrhea, and difficulty sleeping. It lowers your immune system so you are more prone to infections. if these side effects become serious. Your doctor can prevent and give you relief from the side effects during the treatment. It makes you feel better.

The benefit of Vingraf 0.5mg Capsule

• In the treatment of prevention of transplantation rejection

Vingraf 0.5mg capsule belongs to a group of medicines known as immunosuppressants. Organ rejection happens when your immune system treats the new organ as an occupier and attacks it. This medicine weakens your immune system and reduces the chance of your body attacking the transplanted organ. It is used in combination with other medicines to make it much more likely that your transplant operation will be successful.

Side effects of Vingraf 0.5mg Capsule

Here are Some major and minor side effects of this medicine. But not all side effects need a doctor’s attention. If you observe any side effects become serious, You may consult your doctor.

Some of the common side effects of this medicine include:

Headache

Diarrhea

Dizziness

Nausea or vomiting

Swelling of feet or lower legs

Blurred vision

Sweating

Weight loss 

Back pain

Joint pain

Scaly skin

Loss of appetite

How is the Vingraf 0.5mg Capsule taken?

Take Vingraf 0.5mg Capsule should take at least an hour before or two hours after a meal. You should take it on an empty stomach to get the most benefit. Take this medicine at around the same time every day. Always take this medicine as per your doctor’s consultation. Dose and duration will decide your doctor. You are not allowed to crush, chew and break the medicine. Swallow it as a whole. Drink plenty of water. Do not miss the dose. If you miss a dose skip the missed dose and follow your schedule regularly on the next day. Do not double the dose. Take medicine every day on time as prescribed by your doctor. Much other medicine can affect this medicine so let your doctor know all medication you are using during the treatment.

How does the Vingraf 0.5mg Capsule work?

Vingraf 0.5mg Capsule is an immunosuppressant. It works to suppress your body’s immune system following the transplant of an organ such as the liver, kidney, or heart. This helps your body to accept the new organ as if it were your own.