What is a Vorier 200 mg Tablet?
Vorier 200 mg tablets consist of the active ingredient Voriconazole. It is indicated to treat fungal infections in patients who have undergone bone marrow transplantation. It acts against fungal infections caused by Invasive Aspergillus, Esophageal Candidiasis, Scedosporium, and Fusarium.
What Voriconazole drug is used for?
Voriconazole is manufactured in India by Zydus Cadila. Voriconazole Vorixia 200 mg is sold under the brand name Vfend. It is used in adults and children 2 years of age and older to treat serious fungal infections such as invasive aspergillosis ( a fungal infection that begins in the lungs and spreads through the bloodstream to other organs), esophageal candidiasis ( a type of fungus) infection that may cause white patching in the mouth and throat) and candidemia ( a fungal infection in the blood). It is also used to treat certain other fungal infections when other medications will not work for certain patients. Voriconazole is in a class of antifungal medications called triazoles. It works to slow the growth of the fungi that cause infection.
What is Invasive aspergillosis?
Aspergillosis is an infection caused by Aspergillus, a common mold ( a type of fungus) that lives indoors and outdoors. Most people breathe in Aspergillus spores every day without getting sick. People with a weakened immune system or lung diseases are at a higher risk of developing health problems due to Aspergillus. The types of health problems caused by Aspergillus include allergic reactions, lung infections, and infections in other organs.
- What are the signs and symptoms of Invasive aspergillosis?
Invasive aspergillosis usually occurs in people who are already sick from other medical conditions, so it can be difficult to know which symptoms are related to an Aspergillus infection. The symptoms of invasive aspergillosis in the lungs include:
Coughing up blood
Shortness of breath
Other symptoms can develop if the infection spreads from the lungs to other parts of the body.
What is Esophageal candidiasis?
Esophageal candidiasis is caused by yeast ( a yeast of fungus) called Candida. Candida normally lives on the skin and inside the body, in places such as the mouth, throat, gut, and vagina, without causing any problems. Sometimes Candida can multiply and cause an infection if the environment inside the mouth, throat, or esophagus changes in a way that encourages fungal growth.
Candidiasis in the esophagus ( the tube that connects the throat to the stomach) is called esophagus candidiasis or Candida esophagitis. Esophageal candidiasis is one of the most common infections in people living with HIV/AIDS.
- What are the signs and symptoms of Esophageal Candidiasis?
Candidiasis in the mouth and throat can have many different symptoms including:
White patches on the inner cheeks, tongue, roof of the mouth, and throat
Redness or soreness
Cotton-like feeling in the mouth
Loss of taste
Pain while eating or swallowing
Cracking and redness at the corners of the mouth
Symptoms of candidiasis in the esophagus are usually pain when swallowing and difficulty swallowing.
What is Scedosporium Apiospermum?
Scedosporium apiospermum is a rare cause of infection but it is increasingly being reported among immunocompromised individuals around the world. There are two cases of scedosporium, one of keratitis and the other of nasal polyp both from immunocompetent patients. The two cases were successfully treated with voriconazole. The diseases caused by Scedosporium are diverse, and they range from the respiratory tract to allergic bronchopulmonary reactions. These infections include skin and soft tissue infections.
Keratitis caused by dematiaceous fungi is increasing worldwide and they were reported to account for 10- 15% of all fungal keratitis. They are the third most frequently encountered fungi.
What is a Fusarium?
Fusarium species are ubiquitous and may be found in the soil, air, and plants. Fusarium species can cause mycotoxicosis in humans following ingestion of food that has been populated by the fungal organism. In humans, fusarium species can also cause disease that is localized, focally invasive, or disseminated. It affects immunocompromised individuals with infection of immunocompetent persons. Localized infection includes septic arthritis, cystitis, and brain abscess. In this situation, a good response may be expected after surgery or oral therapy. Disseminated infection occurs when two or more non-contiguous sites are involved. When disseminated, fusarium infection is present therapy with antifungal agents has generally been disappointing with the chances of a successful resolution being enhanced if the neutropenia can be corrected on time.
The salt of Vorier 200 mg Tablet is also available in liquid form to be taken orally. You need to take this drug at least an hour before or after having a meal. Before taking medicine consult your doctor. Dose and duration will be decided by the necessity and need of the patient. It depends on the treatment and may change from time to time. You should take medicine as per your doctor’s advice. This medicine is strictly not recommended for children, pregnant women, and breastfeeding mothers. It takes some weeks and months to get a better result. Do not stop taking the medicine before your doctor’s advice.
The common side effects of this medicine include agitation, anxiety, headache, dry mouth, loss of appetite, nausea, and vomiting. If these side effects become serious, you consult with your doctor. Your doctor can prevent and give you relief from the side effects. You may feel better during the treatment.
Benefits of Vorier 200 mg Tablet
- In the treatment of Severe fungal infection
Vorier 200 mg Tablet works to kill the fungi which can cause serious infections. It usually makes you feel better very quickly but you should continue taking it as prescribed even when you feel better to make sure that all the fungi and yeast causing the infection are killed and do not become resistant.
Side effects of Vorier 200 mg Tablet
Here are Some major and minor side effects of this medicine. But not all side effects need a doctor’s attention. If you observe any side effects become serious, You may consult your doctor.
Some of the common side effects of this medicine include:
Increased sensitivity of the eyes to sunlight
Yellow-colored eyes or skin
How is the Vorier 200 mg Tablet taken?
The salt of Vorier 200 mg Tablet is also available in liquid form to be taken orally. You need to take this drug at least an hour before or after having a meal. The dosage of the medication is decided by your doctor based on your general health and the type of infection you are suffering from. Always take this medicine as per your doctor’s consultation. Dose and duration will decide your doctor. You are not allowed to crush, chew and break the medicine. Swallow it as a whole. Drink plenty of water. Do not miss the dose. If you miss a dose skip the missed dose and follow your schedule regularly on the next day. Do not double the dose. Take medicine every day on time as prescribed by your doctor. Much other medicine can affect this medicine so let your doctor know all medication you are using during the treatment.
How does Vorier 200 mg Tablet work?
Vorier 200 mg Tablet stops the fungus from producing cytochrome enzymes which facilitate the synthesis of a substance called ergosterol. Complete loss of ergosterol in the fungal cell wall may be responsible for the antifungal activity of this medicine.